We know that living with major depressive disorder is never easy. One of the reasons for this is that finding an effective treatment is often difficult.
Many people with depression are prescribed antidepressants that do not provide adequate symptom relief, or only help for a short time. Because symptom relief is necessary to getting the lives of those who suffer from depression back on track, it is important that we continue looking for new and better treatments for depression.
Conducting medical research through studies like this one is how doctors and drug companies like Axsome Therapeutics, Inc. learn new information about potential medications. Participation of study volunteers is an essential part of the process. Please read-on to learn more about this medical research study for adults who are currently experiencing depression and who have tried one or two antidepressants without receiving adequate symptom relief.
The Purpose of this Research Study
In this research study, we will evaluate the effectiveness and safety of an investigational drug for adults who have not adequately responded to 1 or 2 previously prescribed antidepressants.
What to Expect
This treatment resistant depression study will involve up to 10 visits to the study center over a period of about 14 weeks.
During the first visit (the “screening visit”), the study requirements as well as the potential risks of participation will be explained in detail. Those wishing to participate after this explanation will be asked to sign a written consent form. Next, various questions, tests, and examinations will be asked and given to determine eligibility to participate in the study.
All participants enrolled in this depression study will first receive an FDA-approved antidepressant for a
period of six weeks. Then, if eligible, the participants will enter a second period of 6 weeks of treatment
and either continue to receive the FDA-approved antidepressant or be switched to an investigational drug
during one of the visits of the second period.
Health Insurance and Participation Costs
Health Insurance is not required to participate.
All medical examinations and assigned study drugs are provided to qualified participants at no cost. Financial compensation may also be provided to cover time and travel expenses related to the research study.
Privacy and Confidentiality Policy: If you pre-qualify for this research study, you will be given a choice to submit your contact information along with your answers to the preliminary questionnaire to a study clinic conducting this research study for further evaluation. If you make the choice to submit your contact information, your contact information will only be shared with those involved with the medical research study and will not be shared or provided to any other person or business not related to this medical research study. Except as noted above, your name and contact information will not be taken from you and your answers will remain confidential. We will not use your information for any purpose other than to screen you for potential participation in this medical research study. Your answers will be stored electronically and for auditing purposes, any identifying information that you provide to us will remain stored for up to seven years even if you choose not to participate or are not eligible to participate in this medical research study. If you provide your or a friend’s/family member’s email address, the email address will not be provided to anyone other than the person to whom the email was sent as specified in this website. The person in charge of privacy for this website is the Privacy Officer, who may be contacted at The Patient Recruiting Agency, 6207 Bee Cave Road, Suite 288, Austin, Texas 78746 or
to make any updates to your information or to have your information removed.